1) Severe mental illness not responding to at least one standard treatment (i.e., pharmacotherapy or psychotherapy).
The spectrum of these mental illnesses must include at least one of the following diagnoses:

• Depressive syndrome (ICD code(s) F32.0, F32.1, F32.8, F32.9, F33.0, F33.1, F33.8, F33.9), bipolar disorder type 2 (F31.3, F31.4)[JT1] , cyclothymia (F34.0), dysthymia (F34.1), and/or mixed anxiety and depressive disorder (F41.2). This includes secondary depression attendant to other diseases (unless contraindicated).
  
• Generalised anxiety disorder (F41.1) and/or social phobia (F40.1).
  
• Obsessive-compulsive disorder (F42.X).
  
• Eating disorders (F50.X).
  
• Post-traumatic stress disorder (F43.1).
  

2) Level of therapeutic alliance appropriate for ketamine-assisted therapy.

• The client is motivated to cooperate with the therapist(s) and is capable of self-reflection.
  
• 18 years of age or older.